Then his mother and brothers came to him but were unable to join him because of the crowd. He was told, "Your mother and your brothers are standing outside and they wish to see you." He said to them in reply, "My mother and my brothers are those who hear the word of God and act on it.
While he was speaking, a woman from the crowd called out and said to him, "Blessed is the womb that carried you and the breasts that nursed you." He replied, "Rather, blessed are those that hear the word of God and observe it."
(Luke 11 27-28)
It is important to remember that the Blessed Virgin is not so worthy of our love and veneration merely because she is the Mother of God. It would be hard for us to emulate her if her holiness eminated solely from the fact of her privileged position as the Mother of the Saviour.
It is clear that in Jesus' time, many wished to accord His Mother special treatment or honour by virtue only of the fact that she was His Mother. Jesus refused to let His mother, his first and most perfect disciple, be reduced to a holy woman by virtue of her biological relationship with Christ. No rather, he pointed out again and again that the Mother of God is holy and worthy of veneration and emulation precisely because she "hears the word of God and acts on it". Jesus does not want a biological relationship with us, He wants us to hear the word of God and observe it, to be true disciples, as Mary was and is.